Acetone → 1-[2-chloro-4-fluoro-5-(2-propynyloxy)phenyl]-1,4-dihydro-4-ethyl-5H-tetrazol-5-one
Reaction equation
[Br:18][CH2:19][C:20]#[CH:21].[C:22](=[O:23])([O-:24])[O-:25].[CH3:28][C:29](=[O:30])[CH3:31].[Cl:1][c:2]1[c:3](-[n:10]2[n:11][n:12][n:13]([CH2:16][CH3:17])[c:14]2=[O:15])[cH:4][c:5]([OH:9])[c:6]([F:8])[cH:7]1.[K+:26].[K+:27]>>[Cl:1][c:2]1[c:3](-[n:10]2[n:11][n:12][n:13]([CH2:16][CH3:17])[c:14]2=[O:15])[cH:4][c:5]([O:9][CH2:21][C:20]#[CH:19])[c:6]([F:8])[cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-b0c7c1f0aa044effb858605404122f1d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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