4-(Chloromethyl)-1,3-thiazole → N-Methyl-N-{2-[(4-{[3-methyl-4-(1,3-thiazol-4-ylmethoxy)phenyl]amino}quinazolin-5-yl)oxy]ethyl}acetamide
Reaction equation
[Cl:1][CH2:2][c:3]1[n:4][cH:5][s:6][cH:7]1.[OH:8][c:9]1[c:10]([CH3:34])[cH:11][c:12]([NH:15][c:16]2[n:17][cH:18][n:19][c:20]3[cH:21][cH:22][cH:23][c:24]([O:26][CH2:27][CH2:28][N:29]([C:30]([CH3:31])=[O:32])[CH3:33])[c:25]23)[cH:13][cH:14]1>>[CH2:2]([c:3]1[n:4][cH:5][s:6][cH:7]1)[O:8][c:9]1[c:10]([CH3:34])[cH:11][c:12]([NH:15][c:16]2[n:17][cH:18][n:19][c:20]3[cH:21][cH:22][cH:23][c:24]([O:26][CH2:27][CH2:28][N:29]([C:30]([CH3:31])=[O:32])[CH3:33])[c:25]23)[cH:13][cH:14]1Participants
3
Sources & evidence
- ORD record
- ord-bf778de5299744ba8b6e27e8d0d1e653
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…