Methanol → Tert-butyl 4-(4-amino-2-fluorophenyl)piperidine-1-carboxylate

HRID 2133900Notes

Reaction equation

HRID 2133900 reaction equation
[CH3:1][C:2]([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[c:15]([F:21])[cH:16][c:17]([NH2:20])[cH:18][cH:19]2)=[CH:12][CH2:13]1.[CH3:22][OH:23]>>[CH3:1][C:2]([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[c:15]([F:21])[cH:16][c:17]([NH2:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 887MethanolHCID 543049921,1-Dimethylethyl 4-(4-amino-2-fluorophenyl)-3,6-dihydro-1(2h)-pyridinecarboxylate

Product 1

HCID 53981770Tert-butyl 4-(4-amino-2-fluorophenyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-ea8547ce65da4105b88572b13ce66b37
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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