4-(Trifluoromethoxy)aniline → 1-(Tert-butoxycarbonyl)-4-[[4-(trifluoromethoxy)phenyl]amino]piperidine

HRID 2134174Notes

Reaction equation

HRID 2134174 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[F:15][C:16]([O:17][c:18]1[cH:19][cH:20][c:21]([NH2:22])[cH:23][cH:24]1)([F:25])[F:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:22][c:21]2[cH:20][cH:19][c:18]([O:17][C:16]([F:15])([F:25])[F:26])[cH:24][cH:23]2)[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 6008484-(Trifluoromethoxy)anilineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 66237091-(Tert-butoxycarbonyl)-4-[[4-(trifluoromethoxy)phenyl]amino]piperidine

Sources & evidence

ORD record
ord-a8d5cfc4f1954ce584d9b786ad46449f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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