1-(5-Methyl-[1,3,4]oxadiazol-2-yl)-piperidin-4-one → [8-(4-Fluoro-3-trifluoromethyl-phenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[1-(5-methyl-[1,3,4]oxadiazol-2-yl)-piperidin-4-yl]-amine

HRID 2134181Notes

Reaction equation

HRID 2134181 reaction equation
[CH3:1][c:2]1[n:3][n:4][c:5]([N:7]2[CH2:8][CH2:9][C:10](=[O:13])[CH2:11][CH2:12]2)[o:6]1.[F:14][c:15]1[c:16]([C:31]([F:32])([F:33])[F:34])[cH:17][c:18]([CH:21]2[c:22]3[n:23]([n:27][c:28]([NH2:30])[n:29]3)[CH2:24][CH2:25][CH2:26]2)[cH:19][cH:20]1>>[CH3:1][c:2]1[n:3][n:4][c:5]([N:7]2[CH2:8][CH2:9][CH:10]([NH:30][c:28]3[n:27][n:23]4[c:22]([n:29]3)[CH:21]([c:18]3[cH:17][c:16]([C:31]([F:32])([F:33])[F:34])[c:15]([F:14])[cH:20][cH:19]3)[CH2:26][CH2:25][CH2:24]4)[CH2:11][CH2:12]2)[o:6]1

Participants

3

Reactant 2

HCID 583978531-(5-Methyl-[1,3,4]oxadiazol-2-yl)-piperidin-4-oneHCID 673440428-(4-Fluoro-3-trifluoromethyl-phenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine

Product 1

HCID 58397902[8-(4-Fluoro-3-trifluoromethyl-phenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[1-(5-methyl-[1,3,4]oxadiazol-2-yl)-piperidin-4-yl]-amine

Sources & evidence

ORD record
ord-7d65049458fd4cf59ee42dbb00bdb720
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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