2-Methyl-2-(piperazin-1-yl)propanamide → 2-(4-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-methylpropanamide

HRID 2134309Notes

Reaction equation

HRID 2134309 reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6]2[n:7][c:8]([Cl:19])[n:9][c:10]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[c:11]2[n:12]1.[CH3:20][C:21]([C:22](=[O:23])[NH2:24])([CH3:25])[N:26]1[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]1>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]2[n:7][c:8]([Cl:19])[n:9][c:10]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[c:11]2[n:12]1)[N:29]1[CH2:28][CH2:27][N:26]([C:21]([CH3:20])([C:22](=[O:23])[NH2:24])[CH3:25])[CH2:31][CH2:30]1

Participants

3

Reactant 2

HCID 217488412-Methyl-2-(piperazin-1-yl)propanamideHCID 584049784-(6-(Bromomethyl)-2-chloropyrido[3,2-D]pyrimidin-4-YL)morpholine

Product 1

HCID 584049422-(4-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-methylpropanamide

Sources & evidence

ORD record
ord-bad3b25b257f4fa79107bd6e40d9c0ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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