Acetonitrile → Sorafenib

HRID 2134558Notes

Reaction equation

HRID 2134558 reaction equation
[CH3:1][NH:2][C:3](=[O:4])[c:5]1[n:6][cH:7][cH:8][c:9]([O:11][c:12]2[cH:13][cH:14][c:15]([NH:18][C:19]([O-:20])=[O:21])[cH:16][cH:17]2)[cH:10]1.[CH3:34][C:35]#[N:36].[F:22][C:23]([c:24]1[cH:25][c:26]([NH2:27])[cH:28][cH:29][c:30]1[Cl:31])([F:32])[F:33]>>[CH3:1][NH:2][C:3](=[O:4])[c:5]1[n:6][cH:7][cH:8][c:9]([O:11][c:12]2[cH:13][cH:14][c:15]([NH:18][C:19](=[O:21])[NH:27][c:26]3[cH:25][c:24]([C:23]([F:22])([F:32])[F:33])[c:30]([Cl:31])[cH:29][cH:28]3)[cH:16][cH:17]2)[cH:10]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 675744-Chloro-3-(trifluoromethyl)anilineHCID 86648443HCID 86648443, compound

Product 1

HCID 216239Sorafenib

Sources & evidence

ORD record
ord-17e92738116f4cb083a0b4c942fdc566
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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