4-(Azetidin-3-yl)-2,6-dimethylmorpholine → 5-[[1-[[4-Chloro-2-(trifluoromethyl)phenyl]methyl]indazol-5-yl]methylidene]-2-[3-(2,6-dimethylmorpholin-4-yl)azetidin-1-yl]-1,3-thiazol-4-one

HRID 2134561Notes

Reaction equation

HRID 2134561 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([C:28]([F:29])([F:30])[F:31])[c:5]([CH2:6][n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([CH:16]=[C:17]4[C:18](=[O:25])[N:19]=[C:20]([S:22][CH2:23][CH3:24])[S:21]4)[cH:13][cH:14][c:15]23)[cH:26][cH:27]1.[NH:32]1[CH2:33][CH:34]([N:36]2[CH2:37][CH:38]([CH3:43])[O:39][CH:40]([CH3:42])[CH2:41]2)[CH2:35]1>>[Cl:1][c:2]1[cH:3][c:4]([C:28]([F:29])([F:30])[F:31])[c:5]([CH2:6][n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([CH:16]=[C:17]4[C:18](=[O:25])[N:19]=[C:20]([N:32]5[CH2:33][CH:34]([N:36]6[CH2:37][CH:38]([CH3:43])[O:39][CH:40]([CH3:42])[CH2:41]6)[CH2:35]5)[S:21]4)[cH:13][cH:14][c:15]23)[cH:26][cH:27]1

Participants

3

Reactant 2

HCID 627859194-(Azetidin-3-yl)-2,6-dimethylmorpholineHCID 672401235-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one

Product 1

HCID 767562845-[[1-[[4-Chloro-2-(trifluoromethyl)phenyl]methyl]indazol-5-yl]methylidene]-2-[3-(2,6-dimethylmorpholin-4-yl)azetidin-1-yl]-1,3-thiazol-4-one

Sources & evidence

ORD record
ord-8b2438ab82e74b2f919396852fdb9d7d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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