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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 213466Generated: October 30, 2026

Dichloromethane → 3-chloro-4-(9'-cyclopentyl-5'-methyl-6'-oxo-5',6',8',9'-tetrahydrospiro[cyclopropane-1,7'-pyrimido[5,4-b][1,4]diazepine]-2'-ylamino)-N-(2-dimethylaminoethyl)benzamide

https://huagongshe.com/reaction/213466

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantCarbonate IonHCID 19660—
Reactant1,4-DioxaneHCID 31275—
ReactantCesium cationHCID 104967—
Reactant2-chloro-9-cyclopentyl-8,9-dihydro-5-methylspiro[5H-pyrimido[4,5-b][1,4]diazepine-7,1'-cyclopropan]-6(7H)-oneHCID 57969939—
Reactant4-amino-3-chloro-N-(2-dimethylaminoethyl)benzamideHCID 59763680—
Product3-chloro-4-(9'-cyclopentyl-5'-methyl-6'-oxo-5',6',8',9'-tetrahydrospiro[cyclopropane-1,7'-pyrimido[5,4-b][1,4]diazepine]-2'-ylamino)-N-(2-dimethylaminoethyl)benzamideHCID 68683058—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-7fdea8cc17384cbb939c8fbb7b9e551c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)