Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2134691Generated: October 31, 2026

Dimethylformamide → 2-(3-chloro-4-methanesulfonyl-phenyl)-N-(5-cyano-pyrazin-2-yl)-3-(tetrahydro-pyran-4-yl)-propionamide

https://huagongshe.com/reaction/2134691

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant18-Crown-6HCID 28557—
ReactantN-(5-bromo-pyrazin-2-yl)-2-(3-chloro-4-methanesulfonyl-phenyl)-3-(tetrahydro-pyran-4-yl)-propionamideHCID 9983551—
ReactantHCID 178420554HCID 178420554—
ReactantHCID 178511842HCID 178511842—
Product2-(3-chloro-4-methanesulfonyl-phenyl)-N-(5-cyano-pyrazin-2-yl)-3-(tetrahydro-pyran-4-yl)-propionamideHCID 10478860—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-9c18f446282f4b06b149dd830fcf9f04
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)