2-Thiazolesulfonyl chloride → N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(1-methylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-1,3-thiazole-2-sulfonamide

HRID 2135327Notes

Reaction equation

HRID 2135327 reaction equation
[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:16]3[c:17]([F:23])[c:18]([NH2:19])[cH:20][cH:21][cH:22]3)[n:10][c:11]([CH:13]([CH3:14])[CH3:15])[s:12]2)[n:7]1.[s:24]1[c:25]([S:29](=[O:30])(=[O:31])[Cl:32])[n:26][cH:27][cH:28]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:16]3[c:17]([F:23])[c:18]([NH:19][S:29]([c:25]4[s:24][cH:28][cH:27][n:26]4)(=[O:30])=[O:31])[cH:20][cH:21][cH:22]3)[n:10][c:11]([CH:13]([CH3:14])[CH3:15])[s:12]2)[n:7]1

Participants

3

Reactant 2

HCID 115792352-Thiazolesulfonyl chlorideHCID 579900183-(5-(2-Chloropyrimidin-4-yl)-2-isopropylthiazol-4-yl)-2-fluoroaniline

Product 1

HCID 57989754N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(1-methylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-1,3-thiazole-2-sulfonamide

Sources & evidence

ORD record
ord-c06ceb6f8a4148a180b632ef5b79a1bb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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