HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 6-Benzyloxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 6-Hydroxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid | HCID 19070001 | — |
| Product | 6-Benzyloxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic Acid | HCID 19069973 | — |
Reaction Steps
The 1,2,3,4-tetrahydro-6-hydroxynaphthalene-2-carboxylic acid obtained in the above is caused to react with benzyl bromide in the presence of potassium hydroxide, to obtain 1,2,3,4-tetrahydro-6-benzyloxynaphthalene-2-carboxylic acid. The compound thus obtained is heated under reflux in the presence of an acid catalyst to obtain 1,2,3,4-tetrahydro-6-benzyloxynaphthalene-2-carboxylic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05422039 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-2610e29e13d34bda911c6dcb2de9c970 |
| Source note | uspto-grants-1995_06 |