Pyridine → 3-ethoxy-N-(2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl)prop-2-enamide

HRID 2135436Notes

Reaction equation

HRID 2135436 reaction equation
[CH2:20]([CH3:21])[O:22][CH:23]=[CH:24][C:25](=[O:26])[Cl:27].[Cl:28][CH2:29][Cl:30].[NH2:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[CH2:7][C:6]1([CH2:5]2)[C:11](=[O:19])[NH:12][c:13]2[n:14][cH:15][cH:16][cH:17][c:18]21.[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[NH:1]([c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[CH2:7][C:6]1([CH2:5]2)[C:11](=[O:19])[NH:12][c:13]2[n:14][cH:15][cH:16][cH:17][c:18]21)[C:25]([CH:24]=[CH:23][O:22][CH2:20][CH3:21])=[O:26]

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 30144293-Ethoxy-2-propenoyl chlorideHCID 591667225-amino-1,3-dihydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

Product 1

HCID 775373613-ethoxy-N-(2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl)prop-2-enamide

Sources & evidence

ORD record
ord-903f7707404740aa853b5954603199bf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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