Acetone → 6-(4-Bromo-butoxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester

HRID 2135437Notes

Reaction equation

HRID 2135437 reaction equation
[Br:23][CH2:24][CH2:25][CH2:26][CH2:27][Br:28].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH2:11][c:12]2[cH:13][c:14]([OH:18])[cH:15][cH:16][c:17]21.[CH3:19][C:20](=[O:21])[CH3:22]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH2:11][c:12]2[cH:13][c:14]([O:18][CH2:27][CH2:26][CH2:25][CH2:24][Br:23])[cH:15][cH:16][c:17]21

Participants

4

Reactant 3

HCID 180AcetoneHCID 80561,4-DibromobutaneHCID 53408427Tert-butyl 6-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate

Product 1

HCID 695151816-(4-Bromo-butoxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-2d42aee403c24c63a7a497ad735c65ba
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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