7-fluoro-3-hydroxy-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1-{[5-(trifluoromethyl)-2-furyl]methyl}-1,3-dihydro-2H-indol-2-one → 7-fluoro-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1-{[5-(trifluoromethyl)-2-furyl]methyl}-1,3-dihydro-2H-indol-2-one

HRID 2135479Notes

Reaction equation

HRID 2135479 reaction equation
[CH:1]1([CH2:2][CH2:3][N:4]2[c:5]3[c:6]([cH:7][cH:8][cH:9][cH:10]3)[C:11]([OH:12])([c:13]3[c:14]([OH:15])[cH:16][c:17]4[c:21]([cH:22]3)[O:20][CH2:19][O:18]4)[C:23]2=[O:24])[CH2:25][CH2:26]1.[F:27][c:28]1[cH:29][cH:30][cH:31][c:32]2[c:36]1[N:35]([CH2:37][c:38]1[o:39][c:40]([C:43]([F:44])([F:45])[F:46])[cH:41][cH:42]1)[C:34](=[O:47])[C:33]2([c:48]1[cH:49][c:50]2[c:51]([cH:55][c:56]1[OH:57])[O:52][CH2:53][O:54]2)[OH:58]>>[F:27][c:28]1[cH:29][cH:30][cH:31][c:32]2[c:36]1[N:35]([CH2:37][c:38]1[o:39][c:40]([C:43]([F:44])([F:45])[F:46])[cH:41][cH:42]1)[C:34](=[O:47])[CH:33]2[c:48]1[cH:49][c:50]2[c:51]([cH:55][c:56]1[OH:57])[O:52][CH2:53][O:54]2

Participants

3

Reactant 2

HCID 588725267-fluoro-3-hydroxy-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1-{[5-(trifluoromethyl)-2-furyl]methyl}-1,3-dihydro-2H-indol-2-oneHCID 588725381-(2-cyclopropylethyl)-3-hydroxy-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1,3-dihydro-2H-indol-2-one

Product 1

HCID 588725427-fluoro-3-(6-hydroxy-1,3-benzodioxol-5-yl)-1-{[5-(trifluoromethyl)-2-furyl]methyl}-1,3-dihydro-2H-indol-2-one

Sources & evidence

ORD record
ord-4d85faea65cc4fd3bcab24d6ba0931ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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