Pyridine → 1-[5-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-pyridin-3-yl]-3-(4-chloro-2-methyl-phenyl)-urea

HRID 2135505Notes

Reaction equation

HRID 2135505 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([CH3:11])[c:5]([N:8]=[C:9]=[O:10])[cH:6][cH:7]1.[NH2:12][c:13]1[c:14]2[c:15]([n:16][cH:17][n:18]1)[n:19]([CH:31]([CH3:32])[CH3:33])[cH:20][c:21]2[C:22](=[O:23])[c:24]1[cH:25][n:26][cH:27][c:28]([NH2:30])[cH:29]1.[cH:34]1[cH:35][cH:36][n:37][cH:38][cH:39]1>>[Cl:1][c:2]1[cH:3][c:4]([CH3:11])[c:5]([NH:8][C:9](=[O:10])[NH:30][c:28]2[cH:27][n:26][cH:25][c:24]([C:22]([c:21]3[c:14]4[c:13]([NH2:12])[n:18][cH:17][n:16][c:15]4[n:19]([CH:31]([CH3:32])[CH3:33])[cH:20]3)=[O:23])[cH:29]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 1421574-Chloro-2-methylphenyl isocyanateHCID 68903795(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(5-amino-pyridin-3-yl)-methanone

Product 1

HCID 116483541-[5-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-pyridin-3-yl]-3-(4-chloro-2-methyl-phenyl)-urea

Sources & evidence

ORD record
ord-1b38fc061e6d4f75b131562d9be9c9ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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