4-Chloro-2,5-dimethoxyaniline → 2-chloro-N4-(2,5-dimethoxy-4-chlorophenyl)-5-fluoro-4-pyrimidineamine

HRID 2135890Notes

Reaction equation

HRID 2135890 reaction equation
[CH3:10][O:11][c:12]1[c:13]([NH2:14])[cH:15][c:16]([O:20][CH3:21])[c:17]([Cl:19])[cH:18]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:14][c:13]2[c:12]([O:11][CH3:10])[cH:18][c:17]([Cl:19])[c:16]([O:20][CH3:21])[cH:15]2)[n:7]1

Participants

3

Reactant 2

HCID 228334-Chloro-2,5-dimethoxyanilineHCID 2507052,4-Dichloro-5-fluoropyrimidine

Product 1

HCID 220606222-chloro-N4-(2,5-dimethoxy-4-chlorophenyl)-5-fluoro-4-pyrimidineamine

Sources & evidence

ORD record
ord-90bb59449f3e491a98517bcf21d86f76
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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