Toluene → 2-{(RS)-2-(tert-Butyl-dimethyl-silanyloxy)-1-[(3RS,4SR)-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-ethoxy}-5-chloro-pyridine
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH:21]([CH2:22][O:23][Si:24]([CH3:25])([CH3:26])[C:27]([CH3:28])([CH3:29])[CH3:30])[O:31][c:32]2[n:33][cH:34][c:35]([Cl:38])[cH:36][cH:37]2)[CH:11]([c:13]2[cH:14][c:15]([Cl:20])[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:12]1.[CH3:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[Cl:39][C:40]([O:41][CH:42]([Cl:43])[CH3:44])=[O:45]>>[NH:8]1[CH2:9][CH:10]([CH:21]([CH2:22][O:23][Si:24]([CH3:25])([CH3:26])[C:27]([CH3:28])([CH3:29])[CH3:30])[O:31][c:32]2[n:33][cH:34][c:35]([Cl:38])[cH:36][cH:37]2)[CH:11]([c:13]2[cH:14][c:15]([Cl:20])[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:12]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d6c5c60c533e4f92a4f14ce6b674bb27
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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