Acetonitrile → 5-((4-(7-amino-6-bromo-3-(6-phenylpyridin-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl)cyclohexyl)methyl)-1,3,4-oxadiazol-2(3H)-one
Reaction equation
[Br:43][N:44]1[C:45](=[O:46])[CH2:47][CH2:48][C:49]1=[O:50].[CH3:51][C:52]#[N:53].[NH2:1][c:2]1[cH:3][c:4]([CH:23]2[CH2:24][CH2:25][CH:26]([CH2:29][c:30]3[n:31][nH:32][c:33](=[O:35])[o:34]3)[CH2:27][CH2:28]2)[n:5][c:6]2[n:7]1[n:8][cH:9][c:10]2-[c:11]1[cH:12][n:13][c:14](-[c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[cH:15][cH:16]1.[O-:36][C:37]([C:38]([F:39])([F:40])[F:41])=[O:42]>>[NH2:1][c:2]1[c:3]([Br:43])[c:4]([CH:23]2[CH2:24][CH2:25][CH:26]([CH2:29][c:30]3[n:31][nH:32][c:33](=[O:35])[o:34]3)[CH2:27][CH2:28]2)[n:5][c:6]2[n:7]1[n:8][cH:9][c:10]2-[c:11]1[cH:12][n:13][c:14](-[c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[cH:15][cH:16]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-e84c620766844881a22fdeae1ba87d53
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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