Pyridine → 3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-hydroxyaminomethyl-N-(2-hydroxy-ethoxy)-benzamide
Reaction equation
[BH3:34].[F:1][c:2]1[c:3]([NH:19][c:20]2[c:21]([F:27])[cH:22][c:23]([I:26])[cH:24][cH:25]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH:16]=[N:17][OH:18])[c:14]1[F:15].[OH:35][C:36]([CH:37]([Cl:38])[Cl:39])=[O:40].[n:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[F:1][c:2]1[c:3]([NH:19][c:20]2[c:21]([F:27])[cH:22][c:23]([I:26])[cH:24][cH:25]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH2:16][NH:17][OH:18])[c:14]1[F:15]Participants
5
Sources & evidence
- ORD record
- ord-7937934750d74dd3a2267426b8025882
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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