Ethyl 3-methyl-5-(2-oxo-3-(4-(trifluoromethyl)benzyl)imidazolidin-1-yl)thiophene-2-carboxylate → 2-(3-(Isoquinolin-1-ylmethyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylic acid
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([N:5]2[CH2:6][CH2:7][N:8]([CH2:9][c:10]3[cH:11][cH:12][c:13]([C:14]([F:15])([F:16])[F:17])[cH:18][cH:19]3)[C:20]2=[O:21])[s:22][c:23]1[C:24]([O:25][CH2:26][CH3:27])=[O:28].[c:29]1([CH2:39][N:40]2[C:41](=[O:56])[N:42]([c:45]3[s:46][c:47]([C:51](=[O:52])[O:53][CH2:54][CH3:55])[c:48]([CH3:50])[n:49]3)[CH2:43][CH2:44]2)[n:30][cH:31][cH:32][c:33]2[cH:34][cH:35][cH:36][cH:37][c:38]12>>[c:29]1([CH2:39][N:40]2[C:41](=[O:56])[N:42]([c:45]3[s:46][c:47]([C:51](=[O:52])[OH:53])[c:48]([CH3:50])[n:49]3)[CH2:43][CH2:44]2)[n:30][cH:31][cH:32][c:33]2[cH:34][cH:35][cH:36][cH:37][c:38]12Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d4557ae6f34d44a7a3fbf7069d91c702
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…