1,2-Oxazole-5-carboxylic acid → N-[[6-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-5-fluoro-2-[1-(4-fluorophenyl)ethylamino]-3-pyridinyl]methyl]-1,2-oxazole-5-carboxamide
Reaction equation
[NH2:1][CH2:2][c:3]1[c:4]([NH:19][CH:20]([CH3:21])[c:22]2[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]2)[n:5][c:6]([NH:10][c:11]2[n:12][nH:13][c:14]([CH:16]3[CH2:17][CH2:18]3)[cH:15]2)[c:7]([F:9])[cH:8]1.[o:29]1[n:30][cH:31][cH:32][c:33]1[C:34](=[O:35])[OH:36]>>[NH:1]([CH2:2][c:3]1[c:4]([NH:19][CH:20]([CH3:21])[c:22]2[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]2)[n:5][c:6]([NH:10][c:11]2[n:12][nH:13][c:14]([CH:16]3[CH2:17][CH2:18]3)[cH:15]2)[c:7]([F:9])[cH:8]1)[C:34]([c:33]1[o:29][n:30][cH:31][cH:32]1)=[O:35]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2ba0f5d4391d48b192ff937fab6f0923
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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