4-(2-Aminoethyl)-2-chlorophenol → (3-{2-[2-(3-Chloro-4-hydroxy-phenyl)-ethylamino]-pyrimidin-4-yl}-benzyl)-isopropyl-carbamic acid tert-butyl ester

HRID 2136372Notes

Reaction equation

HRID 2136372 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH:8]([CH3:9])[CH3:10])[CH2:11][c:12]1[cH:13][c:14](-[c:18]2[n:19][c:20]([Cl:24])[n:21][cH:22][cH:23]2)[cH:15][cH:16][cH:17]1)=[O:25].[NH2:26][CH2:27][CH2:28][c:29]1[cH:30][c:31]([Cl:36])[c:32]([OH:35])[cH:33][cH:34]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH:8]([CH3:9])[CH3:10])[CH2:11][c:12]1[cH:13][c:14](-[c:18]2[n:19][c:20]([NH:26][CH2:27][CH2:28][c:29]3[cH:30][c:31]([Cl:36])[c:32]([OH:35])[cH:33][cH:34]3)[n:21][cH:22][cH:23]2)[cH:15][cH:16][cH:17]1)=[O:25]

Participants

3

Reactant 2

HCID 230715554-(2-Aminoethyl)-2-chlorophenolHCID 86603285[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-isopropyl-carbamic acid tert-butyl ester

Product 1

HCID 67044858(3-{2-[2-(3-Chloro-4-hydroxy-phenyl)-ethylamino]-pyrimidin-4-yl}-benzyl)-isopropyl-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-fd30687973a34467bbaca9770b88a50e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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