{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester → {1-[4-(7-Bromo-6-methoxy-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester
Reaction equation
[Br:37][c:38]1[c:39]([O:56][CH3:57])[cH:40][c:41]2[c:42](=[O:55])[c:43]([I:54])[c:44](-[c:48]3[cH:49][cH:50][cH:51][cH:52][cH:53]3)[o:45][c:46]2[cH:47]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19](=[O:20])[c:21]4[c:22]([cH:23][cH:24][c:25]([F:26])[cH:27]4)[o:28][c:29]3-[c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:43]3[c:42](=[O:55])[c:41]4[cH:40][c:39]([O:56][CH3:57])[c:38]([Br:37])[cH:47][c:46]4[o:45][c:44]3-[c:48]3[cH:49][cH:50][cH:51][cH:52][cH:53]3)[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36]Participants
3
Sources & evidence
- ORD record
- ord-d1a0b1e47e9146fca2dc6a2795b9fe2e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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