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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2136422Generated: November 3, 2026

1,4-Dioxane → 2-(2-(4-((6-Chloro-3-pyridinyl)sulfonyl)-2-(1-propyn-1-yl)-1-piperazinyl)-5-pyrimidinyl)-1,1,1,3,3,3-hexafluoro-2-propanol

https://huagongshe.com/reaction/2136422

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-((6-Chloro-3-pyridinyl)sulfonyl)-3-(1-propyn-1-yl)piperazineHCID 77230767—
Reactant2-(2-Chloropyrimidin-5-yl)-1,1,1,3,3,3-hexafluoropropan-2-olHCID 86670348—
Product2-(2-(4-((6-Chloro-3-pyridinyl)sulfonyl)-2-(1-propyn-1-yl)-1-piperazinyl)-5-pyrimidinyl)-1,1,1,3,3,3-hexafluoro-2-propanolHCID 86670417—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-ee3150a4e72b49148774f18971f547d9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)