(3-(1H-pyrazol-1-yl)phenyl)boronic acid → (1RS,3RS)-3-[3-(3-Pyrazol-1-yl-phenyl)-imidazo[1,2-a]pyridin-6-ylamino]-cyclohexanol

HRID 2136574Notes

Reaction equation

HRID 2136574 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]2[n:6]1[cH:7][c:8]([NH:11][CH:12]1[CH2:13][CH:14]([OH:18])[CH2:15][CH2:16][CH2:17]1)[cH:9][cH:10]2.[n:19]1(-[c:24]2[cH:25][c:26]([B:30]([OH:31])[OH:32])[cH:27][cH:28][cH:29]2)[n:20][cH:21][cH:22][cH:23]1>>[c:2]1(-[c:26]2[cH:25][c:24](-[n:19]3[n:20][cH:21][cH:22][cH:23]3)[cH:29][cH:28][cH:27]2)[cH:3][n:4][c:5]2[n:6]1[cH:7][c:8]([NH:11][CH:12]1[CH2:13][CH:14]([OH:18])[CH2:15][CH2:16][CH2:17]1)[cH:9][cH:10]2

Participants

3

Reactant 2

HCID 16640530(3-(1H-pyrazol-1-yl)phenyl)boronic acidHCID 68483082(1RS,3RS)-3-(3-Bromo-imidazo[1,2-a]pyridin-6-ylamino)-cyclohexanol

Product 1

HCID 68487287(1RS,3RS)-3-[3-(3-Pyrazol-1-yl-phenyl)-imidazo[1,2-a]pyridin-6-ylamino]-cyclohexanol

Sources & evidence

ORD record
ord-e637847f21804b2e8204851c79196031
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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