1,3-Diethyl 2-oxopropanedioate → Diethyl 2-[2-(2-ethylaminopyrimidin-4-yl)-2-oxo-ethyl]-2-hydroxymalonate

HRID 2136604Notes

Reaction equation

HRID 2136604 reaction equation
[CH2:1]([CH3:2])[NH:3][c:4]1[n:5][cH:6][cH:7][c:8]([C:10]([CH3:11])=[O:12])[n:9]1.[O:13]=[C:14]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[C:20](=[O:21])[O:22][CH2:23][CH3:24]>>[CH2:1]([CH3:2])[NH:3][c:4]1[n:5][cH:6][cH:7][c:8]([C:10]([CH2:11][C:14]([OH:13])([C:15](=[O:16])[O:17][CH2:18][CH3:19])[C:20](=[O:21])[O:22][CH2:23][CH3:24])=[O:12])[n:9]1

Participants

3

Reactant 2

HCID 691051,3-Diethyl 2-oxopropanedioateHCID 684521251-(2-(Ethylamino)pyrimidin-4-yl)ethanone

Product 1

HCID 68452836Diethyl 2-[2-(2-ethylaminopyrimidin-4-yl)-2-oxo-ethyl]-2-hydroxymalonate

Sources & evidence

ORD record
ord-af29f987f27241698609fbf33c06d902
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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