Chloroform → 3,4-dichloro-N-[1-(5-cyano-4-hydroxy-1,3-thiazol-2-yl)piperidin-4-yl]-5-methyl-1H-pyrrole-2-carboxamide
Reaction equation
[Cl:32][CH2:33][Cl:34].[Cl:35][CH:36]([Cl:37])[Cl:38].[Cl:6][c:7]1[c:8]([C:14](=[O:15])[NH:16][CH:17]2[CH2:18][CH2:19][N:20]([c:23]3[s:24][c:25]([C:30]#[N:31])[c:26]([O:28][CH3:29])[n:27]3)[CH2:21][CH2:22]2)[nH:9][c:10]([CH3:13])[c:11]1[Cl:12].[I:1][Si:2]([CH3:3])([CH3:4])[CH3:5]>>[Cl:6][c:7]1[c:8]([C:14](=[O:15])[NH:16][CH:17]2[CH2:18][CH2:19][N:20]([c:23]3[s:24][c:25]([C:30]#[N:31])[c:26]([OH:28])[n:27]3)[CH2:21][CH2:22]2)[nH:9][c:10]([CH3:13])[c:11]1[Cl:12]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-ee10430ceaf64187a997c5063e51595c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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