4-Methyl-1,3-oxazolidin-2-one → 3-[3,5-Difluoro-4-[4-(5-methyl-2-pyridinyl)piperazine-1-carbonyl]phenyl]-4-methyl-1,3-oxazolidin-2-one

HRID 2136771Notes

Reaction equation

HRID 2136771 reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:24])[c:5]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([CH3:23])[cH:21][cH:22]3)[CH2:15][CH2:16]2)[c:6]([F:8])[cH:7]1.[CH3:25][CH:26]1[NH:27][C:28](=[O:31])[O:29][CH2:30]1>>[c:2]1([N:27]2[CH:26]([CH3:25])[CH2:30][O:29][C:28]2=[O:31])[cH:3][c:4]([F:24])[c:5]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([CH3:23])[cH:21][cH:22]3)[CH2:15][CH2:16]2)[c:6]([F:8])[cH:7]1

Participants

3

Reactant 2

HCID 98554554-Methyl-1,3-oxazolidin-2-oneHCID 58484560(4-Bromo-2,6-difluorophenyl)[4-(5-methylpyridin-2-yl)piperazin-1-yl]methanone

Product 1

HCID 673808023-[3,5-Difluoro-4-[4-(5-methyl-2-pyridinyl)piperazine-1-carbonyl]phenyl]-4-methyl-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-144249c644ce483380eaad8fe14f42d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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