Potassium Cation → methyl 5-[4-(2-fluoro-5-{[(2-fluoro-5-methylphenyl)amino]carbonyl}phenoxy)pyridin-2-yl]-1H-pyrrole-3-carboxylate

HRID 2136829Notes

Reaction equation

HRID 2136829 reaction equation
[C:45](=[O:46])([O-:47])[O-:48].[CH3:27][C:28]1([CH3:29])[C:30]([CH3:31])([CH3:32])[O:33][B:34]([c:35]2[cH:36][c:37]([C:40](=[O:41])[O:42][CH3:43])[cH:38][nH:39]2)[O:44]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]([C:12](=[O:13])[NH:14][c:15]3[c:16]([F:22])[cH:17][cH:18][c:19]([CH3:21])[cH:20]3)[cH:23][cH:24][c:25]2[F:26])[cH:7]1.[Cl:51][CH2:52][Cl:53].[K+:49].[K+:50].[O:55]1[CH2:56][CH2:57][O:58][CH2:59][CH2:60]1.[OH2:54]>>[c:2]1(-[c:35]2[cH:36][c:37]([C:40](=[O:41])[O:42][CH3:43])[cH:38][nH:39]2)[n:3][cH:4][cH:5][c:6]([O:8][c:9]2[cH:10][c:11]([C:12](=[O:13])[NH:14][c:15]3[c:16]([F:22])[cH:17][cH:18][c:19]([CH3:21])[cH:20]3)[cH:23][cH:24][c:25]2[F:26])[cH:7]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 962WaterHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 53405106Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)-1H-pyrrole-3-carboxylateHCID 866515583-(2-Chloropyridin-4-yloxy)-4-fluoro-N-(2-fluoro-5-methylphenyl)benzamide

Product 1

HCID 51001539methyl 5-[4-(2-fluoro-5-{[(2-fluoro-5-methylphenyl)amino]carbonyl}phenoxy)pyridin-2-yl]-1H-pyrrole-3-carboxylate

Sources & evidence

ORD record
ord-8f16864560fa4e8c846fe519ecd83dde
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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