5-Fluoro-2-(trifluoromethyl)benzyl bromide → 1-(5-Fluoro-2-trifluoromethylbenzyl)-7-iodo-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one
Reaction equation
[F:13][c:14]1[cH:15][cH:16][c:17]([C:22]([F:23])([F:24])[F:25])[c:18]([CH2:19][Br:20])[cH:21]1.[I:1][c:2]1[cH:3][c:4]2[c:5]([n:11][cH:12]1)[NH:6][CH2:7][C:8](=[O:10])[NH:9]2>>[I:1][c:2]1[cH:3][c:4]2[c:5]([n:11][cH:12]1)[NH:6][CH2:7][C:8](=[O:10])[N:9]2[CH2:19][c:18]1[c:17]([C:22]([F:23])([F:24])[F:25])[cH:16][cH:15][c:14]([F:13])[cH:21]1Participants
3
Sources & evidence
- ORD record
- ord-7dc56483daee4da9a3ddfe8e1edee5a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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