1-Amino-3-(pyrrolidin-1-yl)propan-2-ol → 4-[5-amino-6-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyrazin-2-yl]-N-(2-hydroxy-3-pyrrolidin-1-ylpropyl)benzamide
Reaction equation
[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:20]2[cH:21][cH:22][c:23]([C:24](=[O:25])[OH:26])[cH:27][cH:28]2)[n:6][c:7]1[O:8][CH:9]([CH3:10])[c:11]1[c:12]([Cl:19])[c:13]([F:18])[cH:14][cH:15][c:16]1[Cl:17].[OH:29][CH:30]([CH2:31][NH2:32])[CH2:33][N:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:20]2[cH:21][cH:22][c:23]([C:24](=[O:26])[NH:32][CH2:31][CH:30]([OH:29])[CH2:33][N:34]3[CH2:35][CH2:36][CH2:37][CH2:38]3)[cH:27][cH:28]2)[n:6][c:7]1[O:8][CH:9]([CH3:10])[c:11]1[c:12]([Cl:19])[c:13]([F:18])[cH:14][cH:15][c:16]1[Cl:17]Participants
3
Sources & evidence
- ORD record
- ord-e368c26728f342bf935c492b7469dd30
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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