Dimethyl Sulfoxide → 4-(2-Chloro-3-pyridinyl)-1-[(4-methoxyphenyl)methyl]piperidine-4-carbonitrile
Reaction equation
[CH3:29][S:30]([CH3:31])=[O:32].[Cl:13][CH2:14][CH2:15][N:16]([CH2:17][CH2:18][Cl:19])[CH2:20][c:21]1[cH:22][cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1[CH2:8][C:9]#[N:10].[H-:12].[Na+:11]>>[Cl:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1[C:8]1([C:9]#[N:10])[CH2:14][CH2:15][N:16]([CH2:20][c:21]2[cH:22][cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]2)[CH2:17][CH2:18]1Participants
6
Sources & evidence
- ORD record
- ord-81a89fd4639348f58b1d9bfb7d0a4e65
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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