Methanol → 3-(Piperidin-4-yl)-4,5-dihydro-1H-benzo[d][1,3]diazepin-2(3H)-one

HRID 2137695Notes

Reaction equation

HRID 2137695 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([N:14]2[C:15](=[O:25])[NH:16][c:17]3[c:18]([cH:21][cH:22][cH:23][cH:24]3)[CH2:19][CH2:20]2)[CH2:12][CH2:13]1.[CH3:28][OH:29].[H:26][H:27]>>[NH:8]1[CH2:9][CH2:10][CH:11]([N:14]2[C:15](=[O:25])[NH:16][c:17]3[c:18]([cH:21][cH:22][cH:23][cH:24]3)[CH2:19][CH2:20]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 887MethanolHCID 162024881,3,4,5-Tetrahydro-3-[1-(phenylmethyl)-4-piperidinyl]-2H-1,3-benzodiazepin-2-oneHCID 178418361HCID 178418361, compound

Product 1

HCID 113795873-(Piperidin-4-yl)-4,5-dihydro-1H-benzo[d][1,3]diazepin-2(3H)-one

Sources & evidence

ORD record
ord-b25c023a7d794ddf852a58ffaa87bde8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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