3-(4-Methylpiperazin-1-yl)aniline → N(8)-(2-Methoxy-benzyl)-N(2)-[3-(4-methyl-piperazin-1-yl)-phenyl]-[1,2,4]triazolo[1,5-a]pyridine-2,8-diamine

HRID 2137701Notes

Reaction equation

HRID 2137701 reaction equation
[CH3:21][N:22]1[CH2:23][CH2:24][N:25]([c:28]2[cH:29][c:30]([NH2:31])[cH:32][cH:33][cH:34]2)[CH2:26][CH2:27]1.[Cl:1][c:2]1[n:3][n:4]2[c:5]([c:6]([NH:10][CH2:11][c:12]3[c:13]([O:18][CH3:19])[cH:14][cH:15][cH:16][cH:17]3)[cH:7][cH:8][cH:9]2)[n:20]1>>[c:2]1([NH:31][c:30]2[cH:29][c:28]([N:25]3[CH2:24][CH2:23][N:22]([CH3:21])[CH2:27][CH2:26]3)[cH:34][cH:33][cH:32]2)[n:3][n:4]2[c:5]([c:6]([NH:10][CH2:11][c:12]3[c:13]([O:18][CH3:19])[cH:14][cH:15][cH:16][cH:17]3)[cH:7][cH:8][cH:9]2)[n:20]1

Participants

3

Reactant 2

HCID 115646133-(4-Methylpiperazin-1-yl)anilineHCID 67479414(2-Chloro-[1,2,4]triazolo[1,5-a]pyridin-8-yl)-(2-methoxy-benzyl)-amine

Product 1

HCID 59612333N(8)-(2-Methoxy-benzyl)-N(2)-[3-(4-methyl-piperazin-1-yl)-phenyl]-[1,2,4]triazolo[1,5-a]pyridine-2,8-diamine

Sources & evidence

ORD record
ord-a685327940ae46e1aa60030f6d8a46e3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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