3-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine → N-(5-(Cyclopropylcarbamoyl)-2-methylphenyl)-4-(5-fluoropyridin-3-yl)-3-methylthiophene-2-carboxamide
Reaction equation
[Br:1][c:2]1[c:3]([CH3:23])[c:4]([C:7](=[O:8])[NH:9][c:10]2[c:11]([CH3:22])[cH:12][cH:13][c:14]([C:16]([NH:17][CH:18]3[CH2:19][CH2:20]3)=[O:21])[cH:15]2)[s:5][cH:6]1.[F:24][c:25]1[cH:26][n:27][cH:28][c:29]([B:31]2[O:32][C:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[O:39]2)[cH:30]1>>[c:2]1(-[c:29]2[cH:28][n:27][cH:26][c:25]([F:24])[cH:30]2)[c:3]([CH3:23])[c:4]([C:7](=[O:8])[NH:9][c:10]2[c:11]([CH3:22])[cH:12][cH:13][c:14]([C:16]([NH:17][CH:18]3[CH2:19][CH2:20]3)=[O:21])[cH:15]2)[s:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-9c32905f96d947a1b97f8818c22fce52
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…