Benzene → Ethyl 4-(4-fluorophenoxy)-3-phenylpiperidine-1-carboxylate

HRID 2137982Notes

Reaction equation

HRID 2137982 reaction equation
[C:22](=[O:23])([O-:24])[O-:25].[Cl:28][C:29](=[O:30])[O:31][CH2:32][CH3:33].[F:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH:7]2[CH:8]([c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[CH2:9][N:10]([CH3:13])[CH2:11][CH2:12]2)[cH:20][cH:21]1.[K+:26].[K+:27].[cH:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH:7]2[CH:8]([c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[CH2:9][N:10]([C:29](=[O:30])[O:31][CH2:32][CH3:33])[CH2:11][CH2:12]2)[cH:20][cH:21]1

Participants

6

Reactant 5

HCID 241BenzeneHCID 813Potassium Cation2×HCID 10928Ethyl chloroformateHCID 19660Carbonate IonHCID 127884664-(4-Fluorophenoxy)-1-methyl-3-phenylpiperidine

Product 1

HCID 12788498Ethyl 4-(4-fluorophenoxy)-3-phenylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-57624d2520424c86a82cec0a7570667c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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