Dimethyl Sulfoxide → 7-Chloro-3-(1-imidazolylmethyl)-2-methylimidazo[2,1-a]isoquinoline

HRID 2138057Notes

Reaction equation

[CH3:1][CH2:2][OH:3].[CH3:35][S:36](=[O:37])[CH3:38].[CH3:4][O:5][S:6]([O-:7])(=[O:8])=[O:9].[Cl:10][c:11]1[c:12]2[cH:13][cH:14][n:15]3[c:16]([c:17]2[cH:18][cH:19][cH:20]1)[n:21][c:22]([CH3:29])[c:23]3[CH2:24][N+:25]([CH3:26])([CH3:27])[CH3:28].[nH:30]1[cH:31][n:32][cH:33][cH:34]1>>[Cl:10][c:11]1[c:12]2[cH:13][cH:14][n:15]3[c:16]([c:17]2[cH:18][cH:19][cH:20]1)[n:21][c:22]([CH3:29])[c:23]3[CH2:24][c:31]1[nH:30][cH:34][cH:33][n:32]1

Participants

Reactant 5

HCID 679Dimethyl Sulfoxide

HCID 702Ethanol

HCID 795Imidazole

HCID 4694097Methyl sulfate(1-)

HCID 13821865(7-Chloro-2-methylimidazo[2,1-a]isoquinolin-3-yl)methyl-trimethylazanium

Product 1

HCID 704198067-Chloro-3-(1-imidazolylmethyl)-2-methylimidazo[2,1-a]isoquinoline

Sources & evidence

ORD record: ord-a71a258598e449de8269b3c7214c39ef
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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