4-Methyloxybenzyl chloride → tert-butyl (3RS,4RS,5SR)-4-(4-chloro-phenyl)-3-(4-methoxy-benzyloxy)-5-propyl-piperidine-1-carboxylate
Reaction equation
[CH3:25][O:26][c:27]1[cH:28][cH:29][c:30]([CH2:31][Cl:32])[cH:33][cH:34]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([OH:24])[CH2:10][N:11]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:12][CH:13]2[CH2:14][CH2:15][CH3:16])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH:9]([O:24][CH2:31][c:30]3[cH:29][cH:28][c:27]([O:26][CH3:25])[cH:34][cH:33]3)[CH2:10][N:11]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:12][CH:13]2[CH2:14][CH2:15][CH3:16])[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-1ea0f242d357454fabb3c932fb616040
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…