1-(2-Diethylaminoethyl)-4-trifluoromethyl-6-iodo-3-hydroxy-3-(2-chlorophenyl)oxindole → 1-(2-Diethylaminoethyl)-4-trifluoromethyl-6-(4-morpholinocarbonyl-1-butynyl)-3-hydroxy-3-(2-chlorophenyl)oxindole
Reaction equation
[CH2:1]([CH3:2])[N:3]([CH2:4][CH2:5][N:6]1[C:7](=[O:28])[C:8]([c:20]2[c:21]([Cl:26])[cH:22][cH:23][cH:24][cH:25]2)([OH:27])[c:9]2[c:10]([C:16]([F:17])([F:18])[F:19])[cH:11][c:12]([I:15])[cH:13][c:14]21)[CH2:29][CH3:30].[O:31]1[CH2:32][CH2:33][N:34]([C:37](=[O:38])[CH2:39][CH2:40][C:41]#[CH:42])[CH2:35][CH2:36]1>>[CH2:1]([CH3:2])[N:3]([CH2:4][CH2:5][N:6]1[C:7](=[O:28])[C:8]([c:20]2[c:21]([Cl:26])[cH:22][cH:23][cH:24][cH:25]2)([OH:27])[c:9]2[c:10]([C:16]([F:17])([F:18])[F:19])[cH:11][c:12]([C:42]#[C:41][CH2:40][CH2:39][C:37]([N:34]3[CH2:33][CH2:32][O:31][CH2:36][CH2:35]3)=[O:38])[cH:13][c:14]21)[CH2:29][CH3:30]Participants
3
Sources & evidence
- ORD record
- ord-5a4f12f3b5ef419a80865e1ae08556d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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