1-(Difluoromethyl)-1H-pyrazole-3-carboxylic acid → N-[3-(2-amino-5,5-difluoro-4-methyl-6H-1,3-oxazin-4-yl)-4-fluorophenyl]-1-(difluoromethyl)pyrazole-3-carboxamide
Reaction equation
[F:19][CH:20]([n:21]1[n:22][c:23]([C:26](=[O:27])[OH:28])[cH:24][cH:25]1)[F:29].[NH2:1][c:2]1[cH:3][cH:4][c:5]([F:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([F:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1)[C:26]([c:23]1[n:22][n:21]([CH:20]([F:19])[F:29])[cH:25][cH:24]1)=[O:27]Participants
3
Sources & evidence
- ORD record
- ord-fb3e226bd9ab461885e8b6c7b92a5fb2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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