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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2138869Generated: November 2, 2026

Hydrochloric Acid → n-[4-Fluoro-3-(trifluoromethyl)phenyl]-1,8,8-trimethyl-2,4-dioxobicyclo[3.2.1]octane-3-carboxamide

https://huagongshe.com/reaction/2138869

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant4-(Dimethylamino)pyridineHCID 14284—
Reactant1,8,8-Trimethylbicyclo[3.2.1]octane-2,4-dioneHCID 137876—
Reactant4-Fluoro-3-(trifluoromethyl)phenyl isocyanateHCID 2733383—
Productn-[4-Fluoro-3-(trifluoromethyl)phenyl]-1,8,8-trimethyl-2,4-dioxobicyclo[3.2.1]octane-3-carboxamideHCID 11596142—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-390ea31d9e9343f5a952d79fcf05f1e0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)