Acetate → ethyl 3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazole-5-carboxylate

HRID 2139034Notes

Reaction equation

HRID 2139034 reaction equation
[C:20]([CH3:21])([CH3:22])([CH3:23])[c:24]1[n:25][nH:26][c:27]([C:29](=[O:30])[O:31][CH2:32][CH3:33])[cH:28]1.[C:37]([O-:38])(=[O:39])[CH3:40].[C:42]([O-:43])(=[O:44])[CH3:45].[Cl:34][CH2:35][Cl:36].[Cu+2:41].[cH:14]1[cH:15][cH:16][n:17][cH:18][cH:19]1.[n:1]1[cH:2][cH:3][cH:4][c:5]2[cH:6][c:7]([B:11]([OH:12])[OH:13])[cH:8][cH:9][c:10]12>>[n:1]1[cH:2][cH:3][cH:4][c:5]2[cH:6][c:7](-[n:26]3[n:25][c:24]([C:20]([CH3:21])([CH3:22])[CH3:23])[cH:28][c:27]3[C:29](=[O:30])[O:31][CH2:32][CH3:33])[cH:8][cH:9][c:10]12

Participants

7

Reactant 6

HCID 175Acetate2×HCID 1049PyridineHCID 6344DichloromethaneHCID 27099Cupric cationHCID 2743509Ethyl 3-tert-butyl-1H-pyrazole-5-carboxylateHCID 4192671Quinolin-6-ylboronic Acid (contains varying amounts of Anhydride)

Product 1

HCID 67251871ethyl 3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazole-5-carboxylate

Sources & evidence

ORD record
ord-0d88b4807cf94c639d4bcac521fa3dfa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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