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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2139299Generated: October 28, 2026

Guaiacol → Tert-butyl 2-[3-acetyl-4-[(3,5-difluorophenyl)methyl]-2,2-dimethyl-1,3-oxazolidin-5-yl]-4-(2-methoxyphenoxy)pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/2139299

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGuaiacolHCID 460—
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantDiisopropyl diazene-1,2-dicarboxylateHCID 75555—
ReactantTert-butyl 2-[3-acetyl-4-[(3,5-difluorophenyl)methyl]-2,2-dimethyl-1,3-oxazolidin-5-yl]-4-hydroxypyrrolidine-1-carboxylateHCID 77558581—
ProductTert-butyl 2-[3-acetyl-4-[(3,5-difluorophenyl)methyl]-2,2-dimethyl-1,3-oxazolidin-5-yl]-4-(2-methoxyphenoxy)pyrrolidine-1-carboxylateHCID 77559015—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-e7b096e34b8d42e58fbac6ab2caec5ef
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)