5-Amino-4-(thiazol-2-yl)thiophene-3-carbonitrile → N-(4-cyano-3-(thiazol-2-yl)thiophen-2-yl)-2-(2-oxo-3,4-dihydro-1,5-naphthyridin-1(2H)-yl)acetamide
Reaction equation
[NH2:1][c:2]1[c:3](-[c:9]2[s:10][cH:11][cH:12][n:13]2)[c:4]([C:7]#[N:8])[cH:5][s:6]1.[O:14]=[C:15]1[N:16]([CH2:25][C:26](=[O:27])[OH:28])[c:17]2[cH:18][cH:19][cH:20][n:21][c:22]2[CH2:23][CH2:24]1>>[NH:1]([c:2]1[c:3](-[c:9]2[s:10][cH:11][cH:12][n:13]2)[c:4]([C:7]#[N:8])[cH:5][s:6]1)[C:26]([CH2:25][N:16]1[C:15](=[O:14])[CH2:24][CH2:23][c:22]2[c:17]1[cH:18][cH:19][cH:20][n:21]2)=[O:27]Participants
3
Sources & evidence
- ORD record
- ord-3f35d406bd1844e684ca4f1f2e4466da
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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