2,2-dimethyl-N-[2-methyl-2-(4-nitro-1H-imidazol-1-yl)propyl]propan-1-amine → 2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-yl]-2-phenylacetamide

HRID 213962Notes

Reaction equation

HRID 213962 reaction equation
[CH3:1][C:2]([CH2:3][NH:4][CH2:5][C:6]([CH3:7])([CH3:8])[CH3:9])([CH3:10])[n:11]1[cH:12][n:13][c:14]([N+:16]([O-:17])=[O:18])[cH:15]1.[F:19][c:20]1[cH:21][c:22]([CH2:27][C:28](=[O:29])[NH:30][CH:31]([C:32](=[O:33])[OH:34])[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:23][c:24]([F:26])[cH:25]1>>[CH3:1][C:2]([CH2:3][NH:4][CH2:5][C:6]([CH3:7])([CH3:8])[CH3:9])([CH3:10])[n:11]1[cH:12][n:13][c:14]([NH:16][C:32]([CH:31]([NH:30][C:28]([CH2:27][c:22]2[cH:21][c:20]([F:19])[cH:25][c:24]([F:26])[cH:23]2)=[O:29])[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)=[O:33])[cH:15]1

Participants

3

Reactant 2

HCID 671640862,2-dimethyl-N-[2-methyl-2-(4-nitro-1H-imidazol-1-yl)propyl]propan-1-amineHCID 775031002-[[2-(3,5-Difluorophenyl)acetyl]amino]-2-phenylacetic acid

Product 1

HCID 684617232-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-yl]-2-phenylacetamide

Sources & evidence

ORD record
ord-2e29f8eb92044975aaf4c673545584ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…