Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2139957Generated: November 1, 2026

Water → 8-fluoro-4,5-dihydro-3-[(1-hydroxycyclobutyl)-ethynyl]-5-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-one

https://huagongshe.com/reaction/2139957

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantHexaneHCID 8058—
ReactantHexamethylphosphoramideHCID 12679—
ReactantCyclobutanoneHCID 14496—
Reactant3-ethynyl-8-fluoro-4,5-dihydro-5-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-oneHCID 19851546—
ReactantButyllithiumHCID 178418339—
Product8-fluoro-4,5-dihydro-3-[(1-hydroxycyclobutyl)-ethynyl]-5-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-oneHCID 70394315—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-3597645415494fd0aa5306ab5bcefebb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)