1-(p-Methoxyphenyl)-2-propanone → N-[5-(4-Fluoro-3-sulfamoyl-phenyl)-4-methyl-thiazol-2-yl]-acetamide

HRID 2140306Notes

Reaction equation

HRID 2140306 reaction equation
[CH3:27][O:28][c:29]1[c:30]([S:45]([NH2:46])(=[O:47])=[O:48])[cH:31][c:32](-[c:35]2[c:36]([CH3:44])[n:37][c:38]([NH:40][C:41]([CH3:42])=[O:43])[s:39]2)[cH:33][cH:34]1.[CH3:49][O:50][c:51]1[cH:52][cH:53][c:54]([CH2:55][C:56](=[O:57])[CH3:58])[cH:59][cH:60]1.[F:12][c:13]1[cH:14][cH:15][c:16]([CH2:17][C:18](=[O:19])[CH3:20])[cH:21][c:22]1[S:23]([Cl:24])(=[O:25])=[O:26].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][C:7](=[O:8])[CH3:9])[cH:10][cH:11]1>>[F:1][c:29]1[c:30]([S:45]([NH2:46])(=[O:47])=[O:48])[cH:31][c:32](-[c:35]2[c:36]([CH3:44])[n:37][c:38]([NH:40][C:41]([CH3:42])=[O:43])[s:39]2)[cH:33][cH:34]1

Participants

5

Reactant 4

HCID 312311-(p-Methoxyphenyl)-2-propanoneHCID 521187(4-Fluorophenyl)acetoneHCID 858617322-Fluoro-5-(2-oxo-propyl)-benzenesulfonyl chlorideHCID 86598407N-[5-(4-Methoxy-3-sulfamoyl-phenyl)-4-methyl-thiazol-2-yl]-acetamide

Product 1

HCID 85861686N-[5-(4-Fluoro-3-sulfamoyl-phenyl)-4-methyl-thiazol-2-yl]-acetamide

Sources & evidence

ORD record
ord-459597ffc1974f58a77af42c0a3e048a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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