(RS)-3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionic acid tert-butyl ester → (RS)-[5-(Cyclopropylmethyl-methyl-amino)-2-(3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionylamino)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:24])[cH:10][c:11]([C:20]([F:21])([F:22])[F:23])[c:12]([N:14]([CH3:15])[CH2:16][CH:17]2[CH2:18][CH2:19]2)[cH:13]1)=[O:25].[C:26]([CH3:28])([CH3:29])([O:30][C:31](=[O:27])[CH2:32][C:33]([c:34]1[cH:35][c:36](-[n:40]2[n:41][n:42][cH:43][c:44]2[CH2:45][O:46][CH:47]2[O:48][CH2:49][CH2:50][CH2:51][CH2:52]2)[cH:37][cH:38][cH:39]1)=[O:53])[CH3:54]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:24][C:31](=[O:30])[CH2:32][C:33]([c:34]2[cH:35][c:36](-[n:40]3[n:41][n:42][cH:43][c:44]3[CH2:45][O:46][CH:47]3[O:48][CH2:49][CH2:50][CH2:51][CH2:52]3)[cH:37][cH:38][cH:39]2)=[O:53])[cH:10][c:11]([C:20]([F:21])([F:22])[F:23])[c:12]([N:14]([CH3:15])[CH2:16][CH:17]2[CH2:18][CH2:19]2)[cH:13]1)=[O:25]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-829ce3b54af84900ac4f88f79f957a7a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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