2-Chloro-N,N-dimethylethylamine → (RS)-1-{2-[1-(2-Dimethylamino-ethyl)-5,6-difluoro-1H-benzoimidazol-2-ylmethyl]-piperidin-1-yl}-1-[5-(4-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone
Reaction equation
[Cl:34][CH2:35][CH2:36][N:37]([CH3:38])[CH3:39].[F:1][c:2]1[cH:3][c:4]2[c:5]([nH:6][c:7]([CH2:9][CH:10]3[N:11]([C:16](=[O:17])[c:18]4[n:19][c:20]([CH3:30])[s:21][c:22]4-[c:23]4[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]4)[CH2:12][CH2:13][CH2:14][CH2:15]3)[n:8]2)[cH:31][c:32]1[F:33]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH2:35][CH2:36][N:37]([CH3:38])[CH3:39])[c:7]([CH2:9][CH:10]3[N:11]([C:16](=[O:17])[c:18]4[n:19][c:20]([CH3:30])[s:21][c:22]4-[c:23]4[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]4)[CH2:12][CH2:13][CH2:14][CH2:15]3)[n:8]2)[cH:31][c:32]1[F:33]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-74169f242b6e4cf0ad5fd6228d65cb0f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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